Desloratadine is loratadine in which the ethoxycarbonyl group attached to the piperidine ring is replaced by hydrogen. The major metabolite of loratidine, desloratadine is an antihistamine that is used for the symptomatic relief of allergic conditions including rhinitis and chronic urticaria. It does not readily enter the central nervous system, so does not cause drowsiness. Among its listed roles, it functions as a H1-receptor antagonist, an anti-allergic agent, a cholinergic antagonist and a drug metabolite. Its therapeutic use is listed as antihistamines. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Clarinex, Aerius, Azomyr, Denosin and Opulis. Its PubChem CID is 124087.
Desloratadine
| CAS No | 100643-71-8 |
|---|---|
| Molecular Formula | C19H19ClN2 |
| Molecular Weight | 310.8 g/mol |
| Synonyms | 13-chloro-2-piperidin-4-ylidene-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene |
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Desloratadine is loratadine in which the ethoxycarbonyl group attached to the piperidine ring is replaced by hydrogen. The major metabolite of loratidine, desloratadine is an antihistamine that is used for the symptomatic relief of allergic conditions including rhinitis and chronic urticaria.
The listed CAS number is 100643-71-8.
The listed molecular formula is C19H19ClN2.
The listed molecular weight is 310.8 g/mol.
13-chloro-2-piperidin-4-ylidene-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene.
The source lists Clarinex, Aerius, Azomyr, Denosin and Opulis.