Decitabine is a hypomethylating agent used to treat myelodysplastic syndromes and acute myeloid leukemia. It inhibits DNA methyltransferase, leading to hypomethylation of DNA and reactivation of silenced genes. It is grouped under the following drug class(es): Antineoplastic agents, Cytotoxics, Nucleosides and Sickle cell agents. Its therapeutic use is listed as anti-cancer agents and antineoplastics. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include AzadC, Dacogen and Dac. Its PubChem CID is 451668.
Decitabine
| CAS No | 2353-33-5 |
|---|---|
| Molecular Formula | C8H12N4O4 |
| Molecular Weight | 228.21 g/mol |
| Synonyms | 4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one |
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Decitabine is a hypomethylating agent used to treat myelodysplastic syndromes and acute myeloid leukemia. It inhibits DNA methyltransferase, leading to hypomethylation of DNA and reactivation of silenced genes.
The listed CAS number is 2353-33-5.
The listed molecular formula is C8H12N4O4.
The listed molecular weight is 228.21 g/mol.
4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one.
The source lists AzadC, Dacogen and Dac.