It serves as the chiral, stable precursor that is reacted with 5-(2-bromoethyl)-2,3-dihydrobenzofuran or 5-(2-tosyloxyethyl)-2,3-dihydrobenzofuran to produce high-purity Darifenacin. Darifenacin alkyl tartrate—specifically, 3-(S)-(+)-(1-carbamoyl-1,1-diphenylmethyl)pyrrolidine L-(+)-tartrate—serves as a key intermediate salt in the synthesis of Darifenacin (an M3 receptor antagonist for overactive bladder) to enhance optical purity and facilitate crystallization, thereby avoiding tedious column chromatography.
Darifenacin_dealkyl_tartrate
| API Name | Darifenacin |
|---|---|
| CAS No | 134002-26-9 |
| Molecular Formula | C22H26N2O7 |
| Molecular Weight | 430.5 g/mol |
| Synonyms | (2R,3R)-2,3-dihydroxybutanedioic acid;2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetamide |
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Frequently Asked Questions
It serves as the chiral, stable precursor that is reacted with 5-(2-bromoethyl)-2,3-dihydrobenzofuran or 5-(2-tosyloxyethyl)-2,3-dihydrobenzofuran to produce high-purity Darifenacin. Darifenacin alkyl tartrate—specifically, 3-(S)-(+)-(1-carbamoyl-1,1-diphenylmethyl)pyrrolidine L-(+)-tartrate—serves as a key intermediate salt in the synthesis of Darifenacin (an M3 receptor antagonist for overactive bladder) to enhance optical purity and facilitate crystallization, thereby avoiding tedious column chromatography.
The CAS number of Darifenacin_dealkyl_tartrate is 134002-26-9.
The molecular formula of Darifenacin_dealkyl_tartrate is C22H26N2O7.
The listed molecular weight of Darifenacin_dealkyl_tartrate is 430.5 g/mol.
Darifenacin_dealkyl_tartrate is listed as being used in connection with the following API: Darifenacin.
The listed synonym or IUPAC name for Darifenacin_dealkyl_tartrate is (2R,3R)-2,3-dihydroxybutanedioic acid;2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetamide.