Daraxonrasib is an orally bioavailable inhibitor of the active, guanosine triphosphate (GTP)-bound form of both wild type and mutant variants of the RAS isoforms, including HRAS, NRAS and KRAS, with potential antineoplastic activity. Other names for this substance include Rasonque and RMC6236 Intermediate 21. Its PubChem CID is 164726578.
Daraxonrasib
| CAS No | 2765081-21-6 |
|---|---|
| Molecular Formula | C44H58N8O5S |
| Molecular Weight | 811.0 g/mol |
| Synonyms | trans-(1S,2S)-N-[(7S,13S)-21-ethyl-20-[2-[(1S)-1-methoxyethyl]-5-(4-methylpiperazin-1-yl)-3-pyridinyl]-17,17-dimethyl-8,14-dioxo-15-oxa-4-thia-9,21,27,28-tetrazapentacyclo[17.5.2.12,5.19,13.022,26]octacosa-1(25),2,5(28),19,22(26),23-hexaen-7-yl]-2-methylcyclopropane-1-carboxamide |
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Daraxonrasib is an orally bioavailable inhibitor of the active, guanosine triphosphate (GTP)-bound form of both wild type and mutant variants of the RAS isoforms, including HRAS, NRAS and KRAS, with potential antineoplastic activity.
The listed CAS number is 2765081-21-6.
The listed molecular formula is C44H58N8O5S.
The listed molecular weight is 811.0 g/mol.
trans-(1S,2S)-N-[(7S,13S)-21-ethyl-20-[2-[(1S)-1-methoxyethyl]-5-(4-methylpiperazin-1-yl)-3-pyridinyl]-17,17-dimethyl-8,14-dioxo-15-oxa-4-thia-9,21,27,28-tetrazapentacyclo[17.5.2.12,5.19,13.022,26]octacosa-1(25),2,5(28),19,22(26),23-hexaen-7-yl]-2-methylcyclopropane-1-carboxamide.
The source lists Rasonque and RMC6236 Intermediate 21.