Dacomitinib monohydrate

Dacomitinib, designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone part of the second-generation tyrosine kinase inhibitors which are characterized by the irreversible binding at the ATP domain of the epidermal growth factor receptor family kinase domains. It is grouped under the following drug class(es): Antineoplastic agents and Kinase inhibitors. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Dacomitinib hydrate and Vizimpro. Its PubChem CID is 70693519.

CAS No 1042385-75-0
Molecular Formula C24H27ClFN5O3
Molecular Weight 488.0 g/mol
Synonyms (E)-N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-piperidin-1-ylbut-2-enamide;hydrate

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