Copper Cu 64 dotatate is a newly approved Cu labeled somatostatin analog and has several advantages over 68Ga-labeled somatostatin analogs for positron emission tomography (PET). Copper Cu 64 dotatate has a longer half-life and can be produced once a day as opposed to several times a day, and lower positron energy lending to improved spatial resolution. Further studies should be performed to compare the two tracers. Further, PET using Copper Cu 64 dotatate has been found to perform better than the current gold standard of single-photon emission computed tomography (SPECT) using 111In-DTPA-octreotide. In a head-to-head trial, the former tracer detected twice as many lesions as the latter. The directory classifies it as a commercial API with a peptide source/manufacturing origin. Other names for this substance include Detectnet and Copper 64-DOTA-tate. Its PubChem CID is 124220636.
Copper Cu 64 dotatate
| CAS No | 1426155-87-4 |
|---|---|
| Molecular Formula | C65H88CuN14O19S2 |
| Molecular Weight | 1497.5 g/mol |
| Synonyms | 2-[4-[2-[[(2R)-1-[[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-[[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl]-7-[(1R)-1-hydroxyethyl]-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicos-19-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]-10-(carboxylatomethyl)-7-(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetate;copper-64(2+) |
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Frequently Asked Questions
Copper Cu 64 dotatate is a newly approved Cu labeled somatostatin analog and has several advantages over 68Ga-labeled somatostatin analogs for positron emission tomography (PET).
The listed CAS number is 1426155-87-4.
The listed molecular formula is C65H88CuN14O19S2.
The listed molecular weight is 1497.5 g/mol.
The source lists Detectnet and Copper 64-DOTA-tate.
It is listed as a commercial API with a peptide origin.