Clomipramine is a dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine that is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias. Among its listed roles, it functions as a serotonergic antagonist, a serotonergic drug, a serotonin uptake inhibitor, an EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor, an antidepressant and an anticoronaviral agent. Functionally, it is related to imipramine. It is the conjugate base of clomipramine(1+). It is grouped under the following drug class(es): Neurotransmitter agents, Psychotropic agents and QTc-prolonging agents. Its therapeutic use is listed as antidepressants and central nervous system (CNS) agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Hydiphen, Clomicalm and Anapramine. Its PubChem CID is 2801.
Clomipramine
| CAS No | 303-49-1 |
|---|---|
| Molecular Formula | C19H23ClN2 |
| Molecular Weight | 314.9 g/mol |
| Synonyms | 3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine |
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Clomipramine is a dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine that is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group.
The listed CAS number is 303-49-1.
The listed molecular formula is C19H23ClN2.
The listed molecular weight is 314.9 g/mol.
3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine.
The source lists Hydiphen, Clomicalm and Anapramine.