Clofarabine is a purine nucleoside antimetabolite used to treat acute lymphoblastic leukemia. It inhibits DNA synthesis, leading to apoptosis of leukemic cells. It is grouped under the following drug class(es): Antineoplastic agents, Cytotoxics and Nucleosides. Its therapeutic use is listed as anti-cancer agents and antineoplastics. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Clolar, Evoltra and Clofarex. Its PubChem CID is 119182.
Clofarabine
| CAS No | 123318-82-1 |
|---|---|
| Molecular Formula | C10H11ClFN5O3 |
| Molecular Weight | 303.68 g/mol |
| Synonyms | (2R,3R,4S,5R)-5-(6-Amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol |
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Frequently Asked Questions
Clofarabine is a purine nucleoside antimetabolite used to treat acute lymphoblastic leukemia. It inhibits DNA synthesis, leading to apoptosis of leukemic cells.
The listed CAS number is 123318-82-1.
The listed molecular formula is C10H11ClFN5O3.
The listed molecular weight is 303.68 g/mol.
(2R,3R,4S,5R)-5-(6-Amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol.
The source lists Clolar, Evoltra and Clofarex.