Cilengitide

Cilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis. The directory classifies it as a discontinued API with a peptide source/manufacturing origin. Other names for this substance include Cilengitida and Cilengitidum. Its PubChem CID is 176873.

CAS No 188968-51-6
Molecular Formula C27H40N8O7
Molecular Weight 588.7 g/mol
Synonyms 2-[(2S,5R,8S,11S)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid

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