Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary medicine. It is marketed by pharmaceutical company Zoetis as Excenel, and is the active ingredient in that company’s Specramast LC (lactating cow formula) product. It is resistant to hydrolysis by beta-lactamase, and has activity against both Gram-positive and Gram-negative bacteria. E. coli strains resistant to ceftiofur have been reported. The metabolite desfurolyceftiofur also has antibiotic activity, consequently the two compounds are measured together to monitor for antibiotic activity in the milk. The directory classifies it as a commercial API with a semi-synthetic source/manufacturing origin. Other names for this substance include Naxcel, Ceftiofurum and Excede. Its PubChem CID is 6328657.
Ceftiofur
| CAS No | 80370-57-6 |
|---|---|
| Molecular Formula | C19H17N5O7S3 |
| Molecular Weight | 523.56 g/mol |
| Synonyms | (6R,7R)-7-{[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino}-3-[(furan-2-carbonyl)sulfanyl]methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
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Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary medicine. It is marketed by pharmaceutical company Zoetis as Excenel, and is the active ingredient in that company's Specramast LC (lactating cow formula) product.
The listed CAS number is 80370-57-6.
The listed molecular formula is C19H17N5O7S3.
The listed molecular weight is 523.56 g/mol.
(6R,7R)-7-{[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino}-3-[(furan-2-carbonyl)sulfanyl]methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid.
The source lists Naxcel, Ceftiofurum and Excede.