Cefotiam Hydrochloride is a semisynthetic, second-generation cephalosporin antibiotic presented as the hydrochloride salt to enhance water solubility and stability for parenteral use. It acts by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins (PBPs), leading to bactericidal activity. Its therapeutic use is listed as anti-infectives, antibacterials and antibiotics. The directory classifies it as a commercial API with a semi-synthetic source/manufacturing origin. Other names for this substance include Ceradon and Abbott-48999. Its PubChem CID is 47896.
Cefotiam hydrochloride
| CAS No | 66309-69-1 |
|---|---|
| Molecular Formula | C18H25Cl2N9O4S3 |
| Molecular Weight | 598.6 g/mol |
| Synonyms | (6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)acetyl]amino]-3-[[1-[2-(dimethylamino)ethyl]tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;dihydrochloride |
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Frequently Asked Questions
Cefotiam Hydrochloride is a semisynthetic, second-generation cephalosporin antibiotic presented as the hydrochloride salt to enhance water solubility and stability for parenteral use.
The listed CAS number is 66309-69-1.
The listed molecular formula is C18H25Cl2N9O4S3.
The listed molecular weight is 598.6 g/mol.
(6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)acetyl]amino]-3-[[1-[2-(dimethylamino)ethyl]tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;dihydrochloride.
The source lists Ceradon and Abbott-48999.