Cefadroxil hemihydrate

Cefadroxil Hemihydrate is the hemihydrate form of cefadroxil, a semi-synthetic, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cefadroxil hemihydrate binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. The directory classifies it as a commercial API with a semi-synthetic source/manufacturing origin. Other names for this substance include UNII-J9CMF6461M and J9CMF6461M. Its PubChem CID is 67173987.

CAS No 119922-85-9
Molecular Formula C32H36N6O11S2
Molecular Weight 744.8 g/mol
Synonyms (6R,7R)-7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate

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