Carubicin is an anthracycline antineoplastic antibiotic isolated from the bacterium Actinomadura carminata. Carubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. It is grouped under the following drug class(es): Anthracyclines. The directory classifies it as a discontinued API with a semi-synthetic source/manufacturing origin. Other names for this substance include Carminomycin, Karminomitsin and Demethyldaunomycin. Its PubChem CID is 443831.
Carubicin
| CAS No | 50935-04-01 |
|---|---|
| Molecular Formula | C26H27NO10 |
| Molecular Weight | 513.5 g/mol |
| Synonyms | (7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-4,6,9,11-tetrahydroxy-8,10-dihydro-7H-tetracene-5,12-dione |
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Carubicin is an anthracycline antineoplastic antibiotic isolated from the bacterium Actinomadura carminata. Carubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis.
The listed CAS number is 50935-04-01.
The listed molecular formula is C26H27NO10.
The listed molecular weight is 513.5 g/mol.
(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-4,6,9,11-tetrahydroxy-8,10-dihydro-7H-tetracene-5,12-dione.
The source lists Carminomycin, Karminomitsin and Demethyldaunomycin.