Carfilzomib is a synthetic tetrapeptide consisting of morpholin-4-acetyl, L-2-amino-4-phenylbutanoyl, L-leucyl and L-phenylalanyl residues joined in sequence with the C-terminus connected to the amino group of (2S)-2-amino-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-1-one via an amide linkage. Used for the treatment of patients with multiple myeloma Among its listed roles, it functions as a antineoplastic agent and a proteasome inhibitor. It is a tetrapeptide, a member of morpholines and an epoxide. It is grouped under the following drug class(es): Antineoplastic agents and Proteasome inhibitors. Its therapeutic use is listed as anti-cancer agents and antineoplastics. The directory classifies it as a commercial API with a peptide source/manufacturing origin. Other names for this substance include Kyprolis (TN) and carfilzomibum. Its PubChem CID is 11556711.
Carfilzomib
| CAS No | 868540-17-4 |
|---|---|
| Molecular Formula | C40H57N5O7 |
| Molecular Weight | 719.9 g/mol |
| Synonyms | (2S)-4-methyl-N-[(2S)-1-[[(2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]-4-phenylbutanoyl]amino]pentanamide |
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Frequently Asked Questions
Carfilzomib is a synthetic tetrapeptide consisting of morpholin-4-acetyl, L-2-amino-4-phenylbutanoyl, L-leucyl and L-phenylalanyl residues joined in sequence with the C-terminus connected to the amino group of (2S)-2-amino-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-1-one via an amide linkage.
The listed CAS number is 868540-17-4.
The listed molecular formula is C40H57N5O7.
The listed molecular weight is 719.9 g/mol.
(2S)-4-methyl-N-[(2S)-1-[[(2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]-4-phenylbutanoyl]amino]pentanamide.
The source lists Kyprolis (TN) and carfilzomibum.