Caldaret (MCC‑135) is a modulator of intracellular Ca²⁺ handling, specifically inhibiting the reverse‑mode Na⁺/Ca²⁺ exchanger. This inhibition helps restore sarcoplasmic reticulum Ca²⁺‑ATPase (SERCA) activity in ischemia‑reperfusion settings, improving calcium dynamics in cardiomyocytes. The directory classifies it as a unknown/inactive API with a synthetic source/manufacturing origin. Other names for this substance include 9L3Y3IJ2HI, DTXSID80158376, 5-methyl-2-(1-piperazinyl) benzenesulfonic acid and caldaretum. Its PubChem CID is 6433076.
Caldaret
| CAS No | 133804-44-1 |
|---|---|
| Molecular Formula | C11H16N2O3S |
| Molecular Weight | 256.32 g/mol |
| Synonyms | 5-methyl-2-piperazin-1-ylbenzenesulfonic acid |
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Caldaret (MCC‑135) is a modulator of intracellular Ca²⁺ handling, specifically inhibiting the reverse‑mode Na⁺/Ca²⁺ exchanger. This inhibition helps restore sarcoplasmic reticulum Ca²⁺‑ATPase (SERCA) activity in ischemia‑reperfusion settings, improving calcium dynamics in cardiomyocytes.
The listed CAS number is 133804-44-1.
The listed molecular formula is C11H16N2O3S.
The listed molecular weight is 256.32 g/mol.
5-methyl-2-piperazin-1-ylbenzenesulfonic acid.
The source lists 9L3Y3IJ2HI, DTXSID80158376, 5-methyl-2-(1-piperazinyl) benzenesulfonic acid and caldaretum.