Calcitriol

Calcitriol is a hydroxycalciol that is calcidiol in which the pro-S hydrogen of calcidiol is replaced by a hydroxy group. It is the active form of vitamin D3, produced fom calciol via hydoxylation in the liver to form calcidiol, that is subsequently oxidised in the kidney to give calcitriol. Among its listed roles, it functions as a bone density conservation agent, an antipsoriatic, an immunomodulator, an antineoplastic agent, a calcium channel modulator, a nutraceutical, a calcium channel agonist, a metabolite, a hormone, a human metabolite and a mouse metabolite. It is a hydroxycalciol, a member of D3 vitamins and a triol. It is grouped under the following drug class(es): Hormones and Vitamins. Its therapeutic use is listed as anti-osteoporosis agents, anti-psoriatic agents and dermatologicals. The directory classifies it as a commercial API with a semi-synthetic source/manufacturing origin. Other names for this substance include Calcijex, Topitriol, 1alpha, 25-Dihydroxyvitamin D3, Rocaltrol and Vectical. Its PubChem CID is 5280453.