Busulfan

Busulfan is a methanesulfonate ester that is butane-1,4-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. An alkylating antineoplastic agent, it is used to treat chronic myeloid leukemia (although it has been largely replaced by newer drugs). It is also used as an insect sterilant. Among its listed roles, it functions as a insect sterilant, an antineoplastic agent, a teratogenic agent, a carcinogenic agent and an alkylating agent. Functionally, it is related to butane-1,4-diol. It is grouped under the following drug class(es): Alkylating agents, Antineoplastic agents, Cytotoxics and Sulfones. Its therapeutic use is listed as anti-cancer agents and antineoplastics. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Myleran, Busulphan and Sulphabutin. Its PubChem CID is 2478.

CAS No 55-98-1
Molecular Formula C6H14O6S2
Molecular Weight 246.30 g/mol
Synonyms 4-methylsulfonyloxybutyl methanesulfonate

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