Bromfenac

Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes. Non-ophthalmic formulations of bromfenac were withdrawn in the US in 1998 due to cases of severe liver toxicity. It is grouped under the following drug class(es): Cyclooxygenase‑1 (COX‑1) Inhibitors, Cyclooxygenase‑2 (COX‑2) Inhibitors and Non-Steroidal Anti-Inflammatory Drugs (NSAID). Its therapeutic use is listed as analgesics, anti-inflammatories and ophthalmic agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Xibrom, Bromfenacum and 2-Amino-3-(4-bromobenzoyl)benzeneacetic acid. Its PubChem CID is 60726.

CAS No 91714-94-2
Molecular Formula C15H12BrNO3
Molecular Weight 334.16 g/mol
Synonyms 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid

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