Bortezomib is l-Phenylalaninamide substituted at the amide nitrogen by a 1-(dihydroxyboranyl)-3-methylbutyl group and at N(alpha) by a pyrazin-2-ylcarbonyl group. It is a dipeptidyl boronic acid that reversibly inhibits the 26S proteasome. Among its listed roles, it functions as a antineoplastic agent, a proteasome inhibitor, a protease inhibitor and an antiprotozoal drug. It is an amino acid amide, a member of pyrazines and a L-phenylalanine derivative. Functionally, it is related to boronic acid. It is grouped under the following drug class(es): Antineoplastic agents and Proteasome inhibitors. Its therapeutic use is listed as anti-cancer agents and antineoplastics. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Velcade, radiciol and bortezomibum. Its PubChem CID is 387447.
Bortezomib
| CAS No | 179324-69-7 |
|---|---|
| Molecular Formula | C19H25BN4O4 |
| Molecular Weight | 384.2 g/mol |
| Synonyms | [(1R)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid |
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Frequently Asked Questions
Bortezomib is l-Phenylalaninamide substituted at the amide nitrogen by a 1-(dihydroxyboranyl)-3-methylbutyl group and at N(alpha) by a pyrazin-2-ylcarbonyl group.
The listed CAS number is 179324-69-7.
The listed molecular formula is C19H25BN4O4.
The listed molecular weight is 384.2 g/mol.
[(1R)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid.
The source lists Velcade, radiciol and bortezomibum.