Bivalirudin trifluoroacetate is a synthetic direct thrombin inhibitor peptide used as an active pharmaceutical ingredient. It binds both free and clot-bound thrombin, inhibiting fibrin formation and thrombin-mediated platelet activation. As an API, it is used in anticoagulant formulations, particularly for patients undergoing percutaneous coronary interventions (PCI) and in those with or at risk of heparin-induced thrombocytopenia (HIT). It is grouped under the following drug class(es): Peptides. Its therapeutic use is listed as hematologic agents. The directory classifies it as a commercial API with a biotechnology source/manufacturing origin. Other names for this substance include Angiox, L-Leucine, D-phenylalanyl-L-prolyl-L-arginyl-L-prolylglycylglycylglycylglycyl-L-asparaginylglycyl-L-alpha-aspartyl-L-phenylalanyl-L-alpha-glutamyl-L-alpha-glutamyl-L-isoleucyl-L-prolyl-L-alpha-glutamyl-L-alpha-glutamyl-L-tyrosyl-, 2, 2 and 2-trifluoroacetate (1:2). Its PubChem CID is 126480209.
Bivalirudin Trifluoroacetate
| CAS No | 1191386-50-1 |
|---|---|
| Molecular Formula | C102H140F6N24O37 |
| Molecular Weight | 2408.3 g/mol |
| Synonyms | (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-4-amino-2-[[2-[[2-[[2-[[2-[[(2S)-1-[(2S)-2-[[(2S)-1-[(2R)-2-amino-3-phenylpropanoyl]pyrrolidine-2-carbonyl]amino]-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]acetyl]amino]acetyl]amino]acetyl]amino]-4-oxobutanoyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]-3-phenylpropanoyl]amino]-4-carboxybutanoyl]amino]-4-carboxybutanoyl]amino]-3-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-4-carboxybutanoyl]amino]-4-carboxybutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoic acid;bis(2,2,2-trifluoroacetic acid) |
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Frequently Asked Questions
Bivalirudin trifluoroacetate is a synthetic direct thrombin inhibitor peptide used as an active pharmaceutical ingredient. It binds both free and clot-bound thrombin, inhibiting fibrin formation and thrombin-mediated platelet activation.
The listed CAS number is 1191386-50-1.
The listed molecular formula is C102H140F6N24O37.
The listed molecular weight is 2408.3 g/mol.
The source lists Angiox, L-Leucine, D-phenylalanyl-L-prolyl-L-arginyl-L-prolylglycylglycylglycylglycyl-L-asparaginylglycyl-L-alpha-aspartyl-L-phenylalanyl-L-alpha-glutamyl-L-alpha-glutamyl-L-isoleucyl-L-prolyl-L-alpha-glutamyl-L-alpha-glutamyl-L-tyrosyl-, 2, 2 and 2-trifluoroacetate (1:2).
Its therapeutic use is listed as hematologic agents.