benzyl (2S,4S)-4-hydroxy-2-(4-methoxycarbonylphenyl)piperidine-1-carboxylate

It often serves to produce the intermediate 15 in the practical, high-yield, seven-step synthesis of the drug. Benzyl (2S,4S)-4-hydroxy-2-(4-methoxycarbonylphenyl)piperidine-1-carboxylate is a key chiral intermediate employed to synthesize Iptacopan, specifically for constructing the (2S, 4S)-piperidine core.

API Name Iptacopan
CAS No 2408761-17-9
Molecular Formula C21H23NO5
Molecular Weight 369.4 g/mol
Synonyms benzyl (2S,4S)-4-hydroxy-2-(4-methoxycarbonylphenyl)piperidine-1-carboxylate