Benzimidazole

These drugs are often synthesized via cyclization reactions, such as between o-phenylenediamine and carboxylic acids, to create agents effective against intestinal nematodes and cestodes. Benzimidazole is the core structural moiety employed to synthesize a broad class of broad-spectrum anthelmintic agents, including albendazole, mebendazole, thiabendazole, fenbendazole, and flubendazole.