Belotecan is a semi-synthetic camptothecin derivative used as an anticancer drug. It functions as a topoisomerase I inhibitor, interfering with DNA replication and transcription, which leads to cancer cell death. Belotecan is mainly used to treat small cell lung cancer (SCLC) and ovarian cancer. It is grouped under the following drug class(es): Cytotoxics and Topoisomerase inhibitors. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Camtobell and 7-(2-(N-Isopropylamino)ethyl)camptothecin. Its PubChem CID is 6456014.
Belotecan
| CAS No | 256411-32-2 |
|---|---|
| Molecular Formula | C25H27N3O4 |
| Molecular Weight | 433.5 g/mol |
| Synonyms | (19S)-19-ethyl-19-hydroxy-10-[2-(propan-2-ylamino)ethyl]-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione |
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Belotecan is a semi-synthetic camptothecin derivative used as an anticancer drug. It functions as a topoisomerase I inhibitor, interfering with DNA replication and transcription, which leads to cancer cell death.
The listed CAS number is 256411-32-2.
The listed molecular formula is C25H27N3O4.
The listed molecular weight is 433.5 g/mol.
(19S)-19-ethyl-19-hydroxy-10-[2-(propan-2-ylamino)ethyl]-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione.
The source lists Camtobell and 7-(2-(N-Isopropylamino)ethyl)camptothecin.