Azelastine hydrochloride

Azelastine hydrochloride is the hydrochloride salt of azelastine. Among its listed roles, it functions as a platelet aggregation inhibitor, a bronchodilator agent, an anti-asthmatic drug, an anti-allergic agent, a H1-receptor antagonist and an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. It includes a azelastine. Azelastine Hydrochloride is the hydrochloride salt form of azelastine, a phthalazinone derivative with antihistaminergic activity. Azelastine hydrochloride competes with histamine for the H1 receptor, thereby diminishing the actions of histamine on effector cells and decreasing the histamine-mediated symptoms of allergic reaction, including bronchoconstriction, vasodilation, increased capillary permeability and spasmodic contractions of gastrointestinal smooth muscle. Its therapeutic use is listed as antihistamines. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Astelin, Optivar, Allergodil and Zalastine. Its PubChem CID is 54360.