Azelaic acid

Nonanedioic acid is an alpha,omega-dicarboxylic acid that is heptane substituted at positions 1 and 7 by carboxy groups. Among its listed roles, it functions as a antibacterial agent, an antineoplastic agent, a dermatologic drug and a plant metabolite. It is a dicarboxylic fatty acid and an alpha,omega-dicarboxylic acid. It is the conjugate acid of azelaate(2-) and an azelaate. Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. It is also produced by Malassezia furfur, also known as Pityrosporum ovale, that is a species of fungus that is normally found on human skin. Azelaic acid is effective against a number of skin conditions, including mild to moderate acne, when applied topically in a cream formulation of 20%. It works in part by stopping the growth of skin bacteria that cause acne, and by keeping skin pores clear. Azelaic acid’s antimicrobial action may be attributable to inhibition of microbial cellular protein synthesis. It is grouped under the following drug class(es): Keratolytics. Its therapeutic use is listed as acne agents and dermatologicals. The directory classifies it as a commercial API with a natural source/manufacturing origin. Other names for this substance include Finacea, Anchoic acid, Lepargylic acid and Skinoren. Its PubChem CID is 2266.

CAS No 123-99-9
Molecular Formula C9H16O4
Molecular Weight 188.22 g/mol
Synonyms nonanedioic acid

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