Aurothioglucose, also known as gold thioglucose, was formerly used to treat rheumatoid arthritis. Contemporary research on the effect of gold salts treatment began in 1935, mainly to reduce inflammation and to slow disease progression in patients with rheumatoid arthritis. The use of gold compounds has decreased since the 1980s owing to numerous side effects, limited efficacy, and slow onset of action. Many if not most gold compounds that were indicated for rheumatoid arthritis therapy have since been replaced with the use of various current disease modifying anti-rheumatic drugs (DMARDs) like methotrexate and others, which are far more effective. Its therapeutic use is listed as antirheumatic agents. The directory classifies it as a discontinued API with a synthetic source/manufacturing origin. Other names for this substance include Auromyose, Aureotan, Brenol, Oronol and Solganol. Its PubChem CID is 6104.
Aurothioglucose
| CAS No | 12192-57-3 |
|---|---|
| Molecular Formula | C6H11AuO5S |
| Molecular Weight | 392.18 g/mol |
| Synonyms | gold(1+);(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxane-2-thiolate |
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Frequently Asked Questions
Aurothioglucose, also known as gold thioglucose, was formerly used to treat rheumatoid arthritis. Contemporary research on the effect of gold salts treatment began in 1935, mainly to reduce inflammation and to slow disease progression in patients with rheumatoid arthritis.
The listed CAS number is 12192-57-3.
The listed molecular formula is C6H11AuO5S.
The listed molecular weight is 392.18 g/mol.
gold(1+);(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxane-2-thiolate.
The source lists Auromyose, Aureotan, Brenol, Oronol and Solganol.