Atamestane has been used in trials studying the treatment of Breast Cancer, Breast Neoplasms, and Neoplasms, Hormone-Dependent. Atamestane is a synthetic steroidal substance with antineoplastic activity. Atamestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. The directory classifies it as a discontinued API with a synthetic source/manufacturing origin. Other names for this substance include Atamestanum and Biomed-777. Its PubChem CID is 57050.
Atamestane
| CAS No | 96301-34-7 |
|---|---|
| Molecular Formula | C20H26O2 |
| Molecular Weight | 298.4 g/mol |
| Synonyms | (8R,9S,10S,13S,14S)-1,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-dione |
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Atamestane has been used in trials studying the treatment of Breast Cancer, Breast Neoplasms, and Neoplasms, Hormone-Dependent. Atamestane is a synthetic steroidal substance with antineoplastic activity.
The listed CAS number is 96301-34-7.
The listed molecular formula is C20H26O2.
The listed molecular weight is 298.4 g/mol.
(8R,9S,10S,13S,14S)-1,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-dione.
The source lists Atamestanum and Biomed-777.