Arundic acid

Arundic acid ((2R)-2-propyloctanoic acid, ONO-2506) is an astrocyte-modulating agent that functions as a neuroprotective agent by inhibiting the synthesis of S100B protein, a calcium-binding protein associated with neurodegenerative diseases and brain injury. It has been investigated in clinical trials for conditions like acute ischemic stroke, Alzheimer’s disease, and Parkinson’s disease, showing promise in experimental models but also raising questions about potential associations with depression. The directory classifies it as a discontinued API with a synthetic source/manufacturing origin. Other names for this substance include Cereact, Proglia and Arocyte. Its PubChem CID is 208925.

CAS No 185517-21-9
Molecular Formula C11H22O2
Molecular Weight 186.29 g/mol
Synonyms (2R)-2-propyloctanoic acid

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