Aminochlorthenoxazine

Aminochlorthenoxazine is an older first-generation antihistamine that was used to treat allergic conditions including allergic rhinitis, urticaria, and general itching. Like many drugs in its class, it worked by blocking H₁ receptors to reduce the effects of histamine, while also producing mild sedation. Although it was once used for symptomatic allergy relief, it is now considered an outdated active pharmaceutical ingredient and has largely been replaced by newer antihistamines that offer better safety and fewer sedative side effects. The directory classifies it as a discontinued API with a synthetic source/manufacturing origin. Other names for this substance include ICI 350, 6-amino-2-(2-chloroethyl)-2, 3-dihydro-1 and 3-benzoxazin-4-one. Its PubChem CID is 18934.