Amikacin

Amikacin is an aminoglycoside antibiotic used to treat severe bacterial infections, including those resistant to other aminoglycosides. It binds to bacterial 30S ribosomal subunits, inhibiting protein synthesis and leading to bacterial cell death. Amikacin is an amino cyclitol glycoside that is kanamycin A acylated at the N-1 position by a 4-amino-2-hydroxybutyryl group. Among its listed roles, it functions as a antimicrobial agent, an antibacterial drug and a nephrotoxic agent. It is an alpha-D-glucoside, an aminoglycoside, a carboxamide and an amino cyclitol glycoside. Functionally, it is related to kanamycin A. It is the conjugate base of amikacin(4+). It is grouped under the following drug class(es): Aminoglycosides. Its therapeutic use is listed as anti-infectives, antibacterials, antibiotics and antituberculars. The directory classifies it as a commercial API with a peptide source/manufacturing origin. Other names for this substance include Potentox, Amicacin and Lukadin. Its PubChem CID is 37768.