Almasilate

Almasilate is a buffering antacid that has been used in peptic ulcers and dyspepsia. It is a crystalline polyhydrate of aluminium/magnesium silicate and mediates its buffering activity by binding hydrogen ions within the polymer. However its therapeutic efficacy is not comparable to other approved antacids, as it is no more effective in neutralizing acid and binding bile salts than other conventional antacids. Given that there are generally more widely available conventional antacids that are just as – if not more – effective than almasilate, almasilate products are only available in certain parts of Europe and/or Asia. It is grouped under the following drug class(es): Antacids. The directory classifies it as a commercial API with a mineral/inorganic source/manufacturing origin. Other names for this substance include Malinal, Megalac and Magnesium aluminosilicate hydrate. Its PubChem CID is 131704329.