Aliskiren

Aliskiren is a monomethoxybenzene compound having a 3-methoxypropoxy group at the 2-position and a multi-substituted branched alkyl substituent at the 4-position. Among its listed roles, it functions as a antihypertensive agent. It is a monomethoxybenzene and a monocarboxylic acid amide. Aliskiren is the first drug in the renin inhibitor drug class and is used to treat hypertension. It was developed by Speedel and Novartis and initially approved by the FDA in early 2007. Aliskiren has been proven to efficacious in reducing blood pressure when used alone or in conjunction with other antihypertensive agents. Its therapeutic use is listed as antihypertensives and cardiovascular. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Rasilez, aliskirenum and Tekturna. Its PubChem CID is 5493444.

CAS No 173334-57-1
Molecular Formula C30H53N3O6
Molecular Weight 551.8 g/mol
Synonyms (2S,4S,5S,7S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-7-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-8-methyl-2-propan-2-ylnonanamide

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