Alfuzosin hydrochloride

Alfuzosin HCl is the hydrochloride salt form of Alfuzosin, enhancing its solubility for oral administration in treating benign prostatic hyperplasia. Alfuzosin Hydrochloride is the hydrochloride salt of alfuzosin, a quinazoline compound with smooth muscle-relaxing activity. Alfuzosin selectively binds to and antagonizes post-synaptic alpha-1-adrenoreceptors in smooth muscle of the prostate, bladder base, bladder neck, prostatic capsule, and prostatic urethra, initiating relaxation of smooth muscle and resulting in improvement of urine flow and the symptoms of benign prostatic hyperplasia (BPH). This agent also blocks alpha-1-adrenoreceptors in peripheral vascular smooth muscle, resulting in vasodilatation and a decrease in peripheral vascular resistance. It is grouped under the following drug class(es): Alpha-1 Blockers. Its therapeutic use is listed as urological agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Uroxatral, Urion, Fuzatal xl, Kelanu xl and Alfetim. Its PubChem CID is 71764.