Afatinib dimaleate is a maleate salt obtained by combining afatinib with two molar equivalents of maleic acid. Used for the first-line treatment of patients with metastatic non-small cell lung cancer. Among its listed roles, it functions as a tyrosine kinase inhibitor and an antineoplastic agent. It includes a afatinib. It is grouped under the following drug class(es): Antineoplastic agents, Kinase inhibitors and Tyrosine Kinase Inhibitors. Its therapeutic use is listed as antineoplastics. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Giotrif, Gilotrif and Afatinib Impurity F. Its PubChem CID is 15606394.
Afatinib dimaleate
| CAS No | 850140-73-7 |
|---|---|
| Molecular Formula | C32H33ClFN5O11 |
| Molecular Weight | 718.1 g/mol |
| Synonyms | bis((Z)-but-2-enedioic acid);(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide |
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Afatinib dimaleate is a maleate salt obtained by combining afatinib with two molar equivalents of maleic acid. Used for the first-line treatment of patients with metastatic non-small cell lung cancer.
The listed CAS number is 850140-73-7.
The listed molecular formula is C32H33ClFN5O11.
The listed molecular weight is 718.1 g/mol.
bis((Z)-but-2-enedioic acid);(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide.
The source lists Giotrif, Gilotrif and Afatinib Impurity F.