Acenocoumarol

Acenocoumarol is an anticoagulant used to prevent and treat thromboembolic diseases. It functions by inhibiting vitamin K epoxide reductase, reducing clotting factor synthesis. Acenocoumarol is a hydroxycoumarin that is warfarin in which the hydrogen at position 4 of the phenyl substituent is replaced by a nitro group. Among its listed roles, it functions as a anticoagulant and an EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor. It is a C-nitro compound, a hydroxycoumarin and a methyl ketone. It is grouped under the following drug class(es): Antithrombotic agents. Its therapeutic use is listed as anticoagulants and hematologic agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Nicoumalone, Sintrom, Zotil and Ascumar. Its PubChem CID is 54676537.

CAS No 152-72-7
Molecular Formula C19H15NO6
Molecular Weight 353.33 g/mol
Synonyms 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]chromen-2-one

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