The avermectins are a series of macrocyclic lactone derivatives with potent anthelmintic properties. A commonly used therapy in recent times has been based on oral or parenteral administration of avermectins, which are macrocyclic lactones produced by fermentation of various, carefully prepared laboratory broths using the soil micro-organism Streptomyces avermitilis. The directory classifies it as a commercial API with a fermentation-derived source/manufacturing origin. Other names for this substance include 5-O-Demethyl-25-de(1-methylpropyl)-25-(1-methylethyl)avermectin A1a and Ivermectin EP Impurity B. It is also listed for alternate use as: API Impurity. Its PubChem CID is 6858005.
Abamectin B1B
| CAS No | 65195-56-4 |
|---|---|
| Molecular Formula | C47H70O14 |
| Molecular Weight | 859.0 g/mol |
| Synonyms | (1′R,2R,3S,4′S,6S,8′R,10′E,12′S,13′S,14′E,16′E,20′R,21′R,24′S)-21′,24′-dihydroxy-12′-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-3,11′,13′,22′-tetramethyl-2-propan-2-ylspiro[2,3-dihydropyran-6,6′-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2′-one |
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Frequently Asked Questions
The avermectins are a series of macrocyclic lactone derivatives with potent anthelmintic properties.
The listed CAS number is 65195-56-4.
The listed molecular formula is C47H70O14.
The listed molecular weight is 859.0 g/mol.
(1′R,2R,3S,4′S,6S,8′R,10′E,12′S,13′S,14′E,16′E,20′R,21′R,24′S)-21′,24′-dihydroxy-12′-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-3,11′,13′,22′-tetramethyl-2-propan-2-ylspiro[2,3-dihydropyran-6,6′-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2′-one.
The source lists 5-O-Demethyl-25-de(1-methylpropyl)-25-(1-methylethyl)avermectin A1a and Ivermectin EP Impurity B.