Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring. In vivo, abacavir sulfate dissociates to its free base, abacavir. It is grouped under the following drug class(es): DNA polymerase inhibitors and Reverse Transcriptase Inhibitors. Its therapeutic use is listed as anti-infectives and antivirals. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Abacavirum and Ziagen. Its PubChem CID is 441300.
Abacavir
| CAS No | 136470-78-5 |
|---|---|
| Molecular Formula | C14H18N6O |
| Molecular Weight | 286.33 g/mol |
| Synonyms | [(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol |
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Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring.
The listed CAS number is 136470-78-5.
The listed molecular formula is C14H18N6O.
The listed molecular weight is 286.33 g/mol.
[(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol.
The source lists Abacavirum and Ziagen.