Its 8‑amino group serves as the reactive site for amide coupling with substituted benzoyl derivatives, forming the benzamide linkage that completes the Pranlukast molecule. The HCl salt form ensures stability and ease of purification, making this intermediate crucial for constructing the pharmacophoric structure of the drug. 8‑Amino‑2‑(2H‑tetrazol‑5‑yl)-4H‑chromen‑4-one hydrochloride is a key intermediate in the synthesis of Pranlukast, providing the essential chromone–tetrazole core.
8-Amino-2-(2H-tetrazol-5-yl)-4H-chromen-4-one hydrochloride
| API Name | Pranlukast |
|---|---|
| CAS No | 110683-23-3 |
| Molecular Formula | C10H8ClN5O2 |
| Molecular Weight | 265.65 g/mol |
| Synonyms | 8-amino-2-(2H-tetrazol-5-yl)chromen-4-one;hydrochloride |
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