It’s also a valuable heterocyclic building block in pharmaceutical research, particularly for developing new neuroactive drugs targeting dopamine receptors for conditions like depression or Parkinson’s, leveraging its core benzazepine structure. 7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one is used mainly as a crucial intermediate in synthesizing Tolvaptan, a medication for low sodium levels (hyponatremia) from heart failure or cirrhosis and SIADH, acting as a vasopressin V2 receptor antagonist.
7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one
| API Name | Tolvaptan |
|---|---|
| CAS No | 137982-91-3 |
| Molecular Formula | C18H15ClN2O4 |
| Molecular Weight | 358.8 g/mol |
| Synonyms | 7-chloro-1-(2-methyl-4-nitrobenzoyl)-3,4-dihydro-2H-1-benzazepin-5-one |
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It's also a valuable heterocyclic building block in pharmaceutical research, particularly for developing new neuroactive drugs targeting dopamine receptors for conditions like depression or Parkinson's, leveraging its core benzazepine structure. 7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one is used mainly as a crucial intermediate in synthesizing Tolvaptan, a medication for low sodium levels (hyponatremia) from heart failure or cirrhosis and SIADH, acting as a vasopressin V2 receptor antagonist.
The CAS number of 7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one is 137982-91-3.
The molecular formula of 7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one is C18H15ClN2O4.
The listed molecular weight of 7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one is 358.8 g/mol.
7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one is listed as being used in connection with the following API: Tolvaptan.
The listed synonym or IUPAC name for 7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one is 7-chloro-1-(2-methyl-4-nitrobenzoyl)-3,4-dihydro-2H-1-benzazepin-5-one.