It serves as a key core structure, typically produced by cyclizing 1-(2,4-dichloropyrimidin-5-yl)ethanone with cyclopentylamine, followed by cyclization and bromination. 6-Bromo-2-chloro-8-cyclopentyl-5-methyl-8H-pyrido(2,3-d)pyrimidin-7-one is a crucial intermediate in the synthesis of Palbociclib (PD 0332991), a CDK4/6 inhibitor used for treating breast cancer.
6-Bromo-2-chloro-8-cyclopentyl-5-methyl-8H-pyrido(2,3-d)pyrimidin-7-one
| API Name | Palbociclib |
|---|---|
| CAS No | 1016636-76-2 |
| Molecular Formula | C13H13BrClN3O |
| Molecular Weight | 342.62 g/mol |
| Synonyms | 6-bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7-one |
Zoho Contact Form - Pharma Intermediates
"*" indicates required fields
Frequently Asked Questions
It serves as a key core structure, typically produced by cyclizing 1-(2,4-dichloropyrimidin-5-yl)ethanone with cyclopentylamine, followed by cyclization and bromination. 6-Bromo-2-chloro-8-cyclopentyl-5-methyl-8H-pyrido(2,3-d)pyrimidin-7-one is a crucial intermediate in the synthesis of Palbociclib (PD 0332991), a CDK4/6 inhibitor used for treating breast cancer.
The CAS number of 6-Bromo-2-chloro-8-cyclopentyl-5-methyl-8H-pyrido(2,3-d)pyrimidin-7-one is 1016636-76-2.
The molecular formula of 6-Bromo-2-chloro-8-cyclopentyl-5-methyl-8H-pyrido(2,3-d)pyrimidin-7-one is C13H13BrClN3O.
The listed molecular weight of 6-Bromo-2-chloro-8-cyclopentyl-5-methyl-8H-pyrido(2,3-d)pyrimidin-7-one is 342.62 g/mol.
6-Bromo-2-chloro-8-cyclopentyl-5-methyl-8H-pyrido(2,3-d)pyrimidin-7-one is listed as being used in connection with the following API: Palbociclib.
The listed synonym or IUPAC name for 6-Bromo-2-chloro-8-cyclopentyl-5-methyl-8H-pyrido(2,3-d)pyrimidin-7-one is 6-bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7-one.