It provides the uracil (pyrimidine) core with an amino group at C6, which is essential for amide bond formation with substituted cinnamic acid derivatives. This intermediate serves as the scaffold for further functionalization, including side-chain attachment and cyclization steps, ultimately leading to the construction of the xanthine-like structure characteristic of Istradefylline and enabling its activity as an adenosine A₂A receptor antagonist. 6-Amino-1,3-diethyl-2,4(1H,3H)-pyrimidinedione is a crucial intermediate in the synthesis of Istradefylline.
6-Amino-1,3-diethyl-2,4(1H,3H)-pyrimidinedione
| API Name | Istradefylline |
|---|---|
| CAS No | 41740-15-2 |
| Molecular Formula | C8H13N3O2 |
| Molecular Weight | 183.21 g/mol |
| Synonyms | 6-amino-1,3-diethylpyrimidine-2,4-dione |
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Frequently Asked Questions
It provides the uracil (pyrimidine) core with an amino group at C6, which is essential for amide bond formation with substituted cinnamic acid derivatives. This intermediate serves as the scaffold for further functionalization, including side-chain attachment and cyclization steps, ultimately leading to the construction of the xanthine-like structure characteristic of Istradefylline and enabling its activity as an adenosine A₂A receptor antagonist. 6-Amino-1,3-diethyl-2,4(1H,3H)-pyrimidinedione is a crucial intermediate in the synthesis of Istradefylline.
The CAS number of 6-Amino-1,3-diethyl-2,4(1H,3H)-pyrimidinedione is 41740-15-2.
The molecular formula of 6-Amino-1,3-diethyl-2,4(1H,3H)-pyrimidinedione is C8H13N3O2.
The listed molecular weight of 6-Amino-1,3-diethyl-2,4(1H,3H)-pyrimidinedione is 183.21 g/mol.
6-Amino-1,3-diethyl-2,4(1H,3H)-pyrimidinedione is listed as being used in connection with the following API: Istradefylline.
The listed synonym or IUPAC name for 6-Amino-1,3-diethyl-2,4(1H,3H)-pyrimidinedione is 6-amino-1,3-diethylpyrimidine-2,4-dione.