This alcohol is converted to its corresponding bromide (e.g., 3-(bromomethyl)-5-methylpyridine) using reagents like thionyl chloride, enabling its coupling with desloratadine to create Rupatadine. (5-Methylpyridin-3-yl)methanol is a crucial intermediate in the chemical synthesis of Rupatadine, an antihistamine, serving as a precursor to the reactive 3-(bromomethyl)-5-methylpyridine used to attach the pyridine ring to the desloratadine scaffold, ultimately forming the final drug molecule.
(5-Methylpyridin-3-yl)methanol
| API Name | Rupatadine |
|---|---|
| CAS No | 102074-19-1 |
| Molecular Formula | C7H9NO |
| Molecular Weight | 123.15 g/mol |
| Synonyms | (5-methyl-3-pyridinyl)methanol |
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