Its uses include helping to introduce necessary functional groups onto the pyrimidine ring structure, allowing for subsequent reactions that form the final drug molecule. 5-Bromouracil is a crucial raw material and key intermediate in the chemical synthesis of Palbociclib (a CDK4/6 inhibitor used for treating breast cancer) and related compounds like Ribociclib and Abemaciclib.
5-Bromouracil
| API Name | Palbociclib |
|---|---|
| CAS No | 51-20-7 |
| Molecular Formula | C4H3BrN2O2 |
| Molecular Weight | 190.98 g/mol |
| Synonyms | 5-bromo-1H-pyrimidine-2,4-dione |
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Frequently Asked Questions
Its uses include helping to introduce necessary functional groups onto the pyrimidine ring structure, allowing for subsequent reactions that form the final drug molecule. 5-Bromouracil is a crucial raw material and key intermediate in the chemical synthesis of Palbociclib (a CDK4/6 inhibitor used for treating breast cancer) and related compounds like Ribociclib and Abemaciclib.
The CAS number of 5-Bromouracil is 51-20-7.
The molecular formula of 5-Bromouracil is C4H3BrN2O2.
The listed molecular weight of 5-Bromouracil is 190.98 g/mol.
5-Bromouracil is listed as being used in connection with the following API: Palbociclib.
The listed synonym or IUPAC name for 5-Bromouracil is 5-bromo-1H-pyrimidine-2,4-dione.