(4R,5R)-3,3-difluoro-5-(hydroxymethyl)oxolane-2,4-diol

It serves as a key intermediate in the synthesis of modified nucleosides and carbohydrate-based therapeutics. The presence of fluorine atoms enhances chemical stability and can significantly influence biological activity. (4R,5R)-3,3-difluoro-5-(hydroxymethyl)oxolane-2,4-diol is a fluorinated furanose analog featuring a difluoromethylene group at the 3-position.

API Name Gemcitabine
CAS No 861445-88-7
Molecular Formula C5H8F2O4
Molecular Weight 170.11 g/mol
Synonyms (4R,5R)-3,3-difluoro-5-(hydroxymethyl)oxolane-2,4-diol

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