Due to the high activity of the chlorines at the 4 and 6 positions (caused by the electron-withdrawing nitro group), this intermediate allows for efficient coupling with chiral cyclopentyl amines, which is essential for building the core structure of Ticagrelor. 4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine is a critical, key intermediate in the synthesis of Ticagrelor, an antiplatelet medication used to prevent cardiovascular events.
4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine
| API Name | Ticagrelor |
|---|---|
| CAS No | 145783-14-8 |
| Molecular Formula | C7H7Cl2N3O2S |
| Molecular Weight | 268.12 g/mol |
| Synonyms | 4,6-dichloro-5-nitro-2-propylsulfanylpyrimidine |
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Frequently Asked Questions
Due to the high activity of the chlorines at the 4 and 6 positions (caused by the electron-withdrawing nitro group), this intermediate allows for efficient coupling with chiral cyclopentyl amines, which is essential for building the core structure of Ticagrelor. 4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine is a critical, key intermediate in the synthesis of Ticagrelor, an antiplatelet medication used to prevent cardiovascular events.
The CAS number of 4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine is 145783-14-8.
The molecular formula of 4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine is C7H7Cl2N3O2S.
The listed molecular weight of 4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine is 268.12 g/mol.
4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine is listed as being used in connection with the following API: Ticagrelor.
The listed synonym or IUPAC name for 4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine is 4,6-dichloro-5-nitro-2-propylsulfanylpyrimidine.