This specific synthesis method involves a N-detosylation step (removal of the p-tolylsulfonyl group) and subsequent alkylation to form the final meperidine structure. 4-Phenyl-1-(p-tolylsulphonyl)piperidine-4-carbonitrile is an intermediate compound that can be used in one potential synthetic route for meperidine hydrochloride, also known as pethidine.
4-Phenyl-1-(p-tolylsulphonyl)piperidine-4-carbonitrile
| API Name | Meperidine hydrochloride |
|---|---|
| CAS No | 24476-55-9 |
| Molecular Formula | C19H20N2O2S |
| Molecular Weight | 340.4 g/mol |
| Synonyms | 1-(4-methylphenyl)sulfonyl-4-phenylpiperidine-4-carbonitrile |
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