4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one

It also serves as a versatile building block for synthesizing complex molecules and exploring new materials, including certain polymers and fine chemicals, by allowing for precise structural modifications. 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one (DMDO-OH) is mainly used in organic synthesis as a key intermediate, especially for creating prodrugs to improve drug delivery, most notably in antihypertensive drugs like Azilsartan medoxomil, by adding a bioreversible carbamate group that enhances bioavailability before being cleaved in the body.

API Name Azilsartan medoxomil
CAS No 91526-18-0
Molecular Formula C5H6O4
Molecular Weight 130.10 g/mol
Synonyms 4-(hydroxymethyl)-5-methyl-1,3-dioxol-2-one

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