4-Chloro-2-(methylthio)pyrimidine-5-carboxylic acid ethyl ester

This combination of functional groups gives the compound high synthetic flexibility. 4-Chloro-2-(methylthio)pyrimidine-5-carboxylic acid ethyl ester is a halogenated pyrimidine derivative used strictly as a synthetic intermediate in pharmaceutical and agrochemical chemistry.The molecule features a pyrimidine heterocyclic core substituted with a chloro group at the 4-position, a methylthio (–SCH₃) group at the 2-position, and an ethyl ester at the 5-carboxylate position.

API Name Avanafil
CAS No 5909-24-0
Molecular Formula C8H9ClN2O2S
Molecular Weight 232.69 g/mol
Synonyms ethyl 4-chloro-2-methylsulfanylpyrimidine-5-carboxylate