It is mainly employed in coupling reactions to form the core intermediate, (R)-3-(4-bromo-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile. 4-Bromopyrazole is a key building block employed to synthesize Ruxolitinib, a JAK1/2 inhibitor, serving as the raw material to introduce the functionalized pyrazole ring.
4-Bromopyrazole
| API Name | Ruxolitinib |
|---|---|
| CAS No | 2075-45-8 |
| Molecular Formula | C3H3BrN2 |
| Molecular Weight | 146.97 g/mol |
| Synonyms | 4-bromo-1H-pyrazole |
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