4-(4-Aminophenoxy)-N-methylpicolinamide

It also serves as an analytical standard, a tracer (deuterated form), and a building block in organic synthesis for developing new targeted therapies and studying biological pathways. 4-(4-Aminophenoxy)-N-methylpicolinamide (APNMP) is used mainly as a key pharmaceutical intermediate in medicinal chemistry, especially for synthesizing anticancer drugs, notably sorafenib (Nexavar) and its structural analogs, by targeting protein kinases like Raf kinase and MET protein to inhibit cancer cell growth and proliferation.

API Name Sorafenib
CAS No 284462-37-9
Molecular Formula C13H13N3O2
Molecular Weight 243.26 g/mol
Synonyms 4-(4-aminophenoxy)-N-methylpyridine-2-carboxamide